ABBV vs VRTX

AbbVie (ABBV) and Vertex Pharmaceuticals (VRTX) compared side by side. AbbVie (ABBV) is larger, with a market cap of $504.8B versus $132.8B for Vertex Pharmaceuticals, about 3.8 times the size. On trailing earnings, VRTX is cheaper at 29.9x versus 80.7x for ABBV.

Head to head

MetricABBVVRTX
Market cap$504.8B$132.8B
P/E (TTM)80.7x29.9x
Forward P/E17.6x25.7x
Revenue (TTM)$64.4B$12.6B
Revenue growth10.2%12.5%
Gross margin72.8%55.0%
Operating margin40.0%38.1%
Free cash flow$18.2B$3.8B
Dividend yield2.42%None
1-year return+28.9%+24.0%
5-year return (annual)+25.6%+23.3%
Max drawdown-45%-92%
FI Handbook gradeBB

Highlighted: the stronger figure on metrics where higher or lower is clearly better.

Growth of $10,000 (5 years, price only)

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ABBVVRTX

ABBV vs VRTX FAQ

Which is bigger, ABBV or VRTX?

AbbVie (ABBV) is larger, with a market cap of $504.8B versus $132.8B for Vertex Pharmaceuticals, about 3.8 times the size.

Is ABBV or VRTX cheaper?

On trailing earnings, VRTX is cheaper at 29.9x versus 80.7x for ABBV. A lower P/E can reflect slower expected growth, so compare growth and margins too.

Which stock performed better over the past year, ABBV or VRTX?

ABBV returned +28.9% over the past year including dividends, versus +24.0% for VRTX, through October 23, 2026.

Which pays a higher dividend, ABBV or VRTX?

ABBV yields 2.42%; VRTX does not pay a dividend.

Full pages: AbbVie · Vertex Pharmaceuticals