MRK vs PFE

Merck (MRK) and Pfizer (PFE) compared side by side. Merck (MRK) is larger, with a market cap of $358.4B versus $171.2B for Pfizer, about 2.1 times the size. On trailing earnings, PFE is cheaper at 39.5x versus 117.2x for MRK.

Head to head

MetricMRKPFE
Market cap$358.4B$171.2B
P/E (TTM)117.2x39.5x
Forward P/E15.7x10.4x
Revenue (TTM)$66.6B$63.7B
Revenue growth5.1%2.6%
Gross margin75.9%74.7%
Operating margin-0.2%27.9%
Free cash flow$16.1B$11.0B
Dividend yield2.34%5.73%
1-year return+71.5%+30.3%
5-year return (annual)+15.8%-1.9%
Max drawdown-69%-69%
FI Handbook gradeCC+

Highlighted: the stronger figure on metrics where higher or lower is clearly better.

Growth of $10,000 (5 years, price only)

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MRKPFE

MRK vs PFE FAQ

Which is bigger, MRK or PFE?

Merck (MRK) is larger, with a market cap of $358.4B versus $171.2B for Pfizer, about 2.1 times the size.

Is MRK or PFE cheaper?

On trailing earnings, PFE is cheaper at 39.5x versus 117.2x for MRK. A lower P/E can reflect slower expected growth, so compare growth and margins too.

Which stock performed better over the past year, MRK or PFE?

MRK returned +71.5% over the past year including dividends, versus +30.3% for PFE, through October 23, 2026.

Which pays a higher dividend, MRK or PFE?

PFE yields 5.73% versus 2.34% for MRK.

Full pages: Merck · Pfizer